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Index > Protein center > NR3C2(Gene name) > Pig
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  • NR3C2 (Gene name),
  • Mineralocorticoid receptor (Protein name ),  MCR_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NR3C2(MLR);
    Protein name:
    Mineralocorticoid receptor(MR);
    Alternative:
    Nuclear receptor subfamily 3 group C member 2;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Heteromultimeric cytoplasmic complex with HSP90, HSP70, and FKBP4, in the absence of ligand. After ligand binding, it translocates to the nucleus and binds to DNA as a homodimer and as a heterodimer with NR3C1. Binds the coactivator NCOA2. May interact with HSD11B2 in the absence of ligand. Binds the coactivators NCOA1, TIF1 and NRIP1.
    Function:
    Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
    Subcellular Location:
    Cytoplasm Nucleus Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.
    Protein Attributes:
    Sequence length:
    164
    Sequence:
    50:
    QYSWMCLSSF | ALSWRSYKHT | NSQFLYFAPD | LVFNEEKMHQ | SAMYELCQGM | 
    100:
    HQISLQFVRL | QLTFEEYTIM | KVLLLLSTIP | KDGLKSQAAF | EEMRTNYIKE | 
    150:
    LRKMVTRCPN | NSGQSWQRFY | QLTKLLDSMH | DLVSDLLEFC | FYTFRESQAL | 
    164:
    KVEFPRCWWR | SSPT
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Pig MR
    Cat.:
    E0158r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Pig MR
    Cat.:
    E0158m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig MR
    Cat.:
    E0158h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Pig MR
    Cat.:
    E0158c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Pig MR
    Cat.:
    E0158p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig MR
    Cat.:
    U0158c
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig MR
    Cat.:
    U0158p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig MR
    Cat.:
    U0158m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig MR
    Cat.:
    U0158h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig MR
    Cat.:
    U0158r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Pig MR
    Polyclonal Antibody for Pig MR
    Cat.:
    P0158Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig MR
    Polyclonal Antibody for Pig MR
    Cat.:
    P0158Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig MR
    Cat.:
    P0158Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig MR
    Monoclonal Antibody for Pig MR
    Monoclonal Antibody for Pig MR
    Monoclonal Antibody for Pig MR
    Monoclonal Antibody for Pig MR
    Protein for Pig MR
    Protein for Pig MR
    Protein for Pig MR
    Protein for Pig MR
    Protein for Pig MR

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    References
    1. 1.
      "Sus scrofa mineralocorticoid receptor partial cDNA; hormone binding domain."
      Perreau V. , Moisan M.P.
      Submitted (1997-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Large white.
      tissue: Kidney.
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